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GERMANTOWN, MD--(Marketwired - Mar 15, 2016) - Orgenesis Inc. (
With regenerative medicine and stem cell becoming more of a popular topic in this field, the scientific program will include the top 50 influential figures and representatives of the top 10 regenerative medicine and stem cell companies, who will be speaking at the event. Professor Sarah Ferber, Ph.D., Founder and Chief Science Officer of Orgenesis, will be speaking March 16, 2016 at Session 1: Frontier of Stem Cell Research.
Diabetes is a prevalent disease affecting over 7 percent of the world's population. Dr. Ferber will be addressing this topic and will discuss cell-based autologous therapy for Diabetes. This presentation will provide insight regarding the technology Orgenesis developed for activating a pancreatic lineage and the beta cell function in adult human liver cells, by transcription factors-induced transdifferentiation. This approach will allow a diabetic patient to overcome both the shortage in tissues available from cadaver and the immune suppression, by becoming a donor of his own therapeutic tissue. Dr. Ferber will discuss how this new approach will allow substantial improvement of diabetic patients' quality of life.
About Orgenesis Inc.
Orgenesis is a cell therapy and regenerative medicine company that is committed to developing a cure for Type 1 Diabetes. In pursuit of this goal, the company has developed and patented a novel technology called "cellular trans-differentiation" that turns an insulin-dependent patient's own liver cells into functional insulin producing cells. Orgenesis has proven that, when exposed ex-vivo to certain pancreatic transcription factors and in specific sequence, human adult liver cells can be transformed into fully functional, beta cell-like insulin producing cells (IPCs). After ex-vivo expansion, the IPCs are re-infused via the portal vein of the diabetic patient. In pre-clinical models of Type 1 Diabetes (Non-Obese Diabetic mice), the re-introduced IPCs remain in the liver, effectively respond to glucose challenge and successfully maintain glycemic homeostasis. In the same NOD model, the implanted IPCs were not subject to auto-immune attack or cellular ablation. Orgenesis plans to initiate P1/2 trials in the next 12-18 months. Orgenesis believes that converting the diabetic patient's own tissue into insulin-producing cells has the potential to overcome the significant issues of donor shortage, cost and exposure to chronic immunosuppressive therapy associated with islet cell transplantation. For more information, visit www.orgenesis.com.
Notice Regarding Forward-Looking Statements
This news release contains "forward-looking statements" which are not purely historical. Such forward-looking statements include, among other things, the expectations of management that our regeneration technology can be developed as therapeutic treatment for diabetes which could, if successful, be a cure for Type 1 Diabetes; that we can develop the technology to turn a small number of cells into a large number of cells; and that we will initiate Phase I and Phase II clinical trials in the near-term. No assurance can be given that any of the events anticipated by the forward-looking statements will occur or, if they do occur, what benefits Orgenesis will obtain from them. Actual results could differ from those projected in any forward-looking statements due to numerous factors, including, among others, the potential failure of development candidates to advance through preclinical studies or demonstrate safety and efficacy in clinical testing; the ability to pass clinical trials so as to move on to the next phase; our technology may not as well as expected, our ability to retain key employees; our ability to finance development and operations; our ability to satisfy the rigorous regulatory requirements for new medical procedures; and competitors may develop better or cheaper alternatives to our products. These forward-looking statements are made as of the date of this news release, and we assume no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements. Investors should refer to the risk factors disclosure outlined in our periodic reports filed from time-to-time with the Securities and Exchange Commission.